Objective:

To evaluate the effectiveness of an automated microfluidic device in recovering additional oocytes from follicular fluid during in vitro fertilization (IVF) and its potential impact on IVF outcomes.

Key Findings:

• The FIND-Chip recovered at least one additional oocyte in over half of the cases, with one case resulting in a live birth from an additional oocyte that was previously discarded.

Interpretation:

The findings suggest that manual screening may overlook viable oocytes, and automated systems like FIND-Chip could enhance oocyte recovery, potentially improving IVF outcomes.

Limitations:

• The study's findings were descriptive due to the small sample size of the pilot return cohort, limiting the ability to generalize results.

Conclusion:

Automated screening technologies may improve IVF laboratory efficiency and outcomes by recovering additional viable oocytes that manual screening may miss, highlighting the need for further research.