June 16, 2026

ACP Suggests First-Line Obesity Drugs

Semaglutide and tirzepatide had the greatest net benefit among evaluated treatments, the committee concluded.

Conexiant

June 15, 2026

Does Weight Loss Intervention Improve Persistent AF?

Randomized trial found significant weight loss did not improve atrial fibrillation severity or burden in older patients with persistent disease.

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June 12, 2026

Combo Therapy May Improve HbA1c in Type 2 Diabetes

Oral orforglipron could be more effective in reducing hemoglobin A1c and body weight, with no increased risk of hypoglycemia in patients with inadequately controlled type 2 diabetes.

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June 11, 2026

When Bad Data Enters the Drug Pipeline

Federal prosecutors allege that a Florida physician and research staff fabricated clinical trial records that were submitted into database systems used to evaluate investigational drugs.

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June 10, 2026

Investigational Drug Shows Potentialin Phase 3 Obesity Trial

In a 76-week randomized trial, patients with obesity without diabetes who received survodutide achieved greater weight loss and favorable changes in several metabolic measures compared with those who received placebo.

Conexiant

June 10, 2026

COPD Severity Tied to Life Expectancy

A pooled US cohort study estimated years of life lost across airflow obstruction severity, including among adults who never smoked.

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June 09, 2026

Side Effects: Context Is the Diagnosis

This week's research makes one thing clear: who someone is before they get sick — their relationships, their partner's health, the back of their eye — is doing a lot of work medicine is only beginning to account for.

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June 09, 2026

Lower BMI, Lower Joint Replacement Risk?

Researchers urge caution in interpreting joint replacement predictors, noting that surgery reflects access and decision-making as well as disease biology.

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June 09, 2026

Semaglutide Tied to Aging Clocks in HIV

A posthoc analysis of a phase 2b trial found favorable changes in DNA methylation–based aging biomarkers among patients with human immunodeficiency virus–associated lipohypertrophy.

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June 05, 2026

Sleep Study Cutoffs May Guide Discharge

Preoperative sleep study values may distinguish lower-risk children within a population for whom overnight admission is currently routine.

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