In Canadian patients with early rheumatoid arthritis, hypertension affected nearly half of the cohort within 5 years - with a striking 34% of males developing new-onset hypertension compared to 21% of females - despite comparable blood pressure rates to the general population at diagnosis.
New study of 1.6M patients reveals bariatric surgery patients show markedly higher medical complexity, with 65.7% having multiple comorbidities compared to 37.7% of GLP-1 RA recipients—suggesting different risk profiles in treatment selection.
Danish study of 4.3 million residents reveals psychiatric patients face up to 6.45 times higher risk of sudden cardiac death, with schizophrenia patients showing the highest hazard ratio of 4.51 compared to the general population.
In a first-of-its-kind study, a single 30-minute light jog reduced 1-hour post-load plasma glucose levels by 9% (from 122.8 to 111.8 mg/dL) in healthy young adults, suggesting even occasional exercise may provide immediate metabolic benefits.
A recent trial in The New England Journal of Medicine shows finerenone significantly reduces total worsening heart failure events, but the reduction in cardiovascular mortality was not statistically significant.
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A recent study revealed associations between cardiometabolic index (CMI), insulin resistance (IR), prediabetes (preDM), and type 2 diabetes mellitus (T2D) in U.S. adults, showing elevated CMI is linked to a higher likelihood of developing IR, preDM, and T2D, with a plateau effect suggesting maintaining CMI at certain levels is beneficial.
Recent study finds that 84% of adults with congenital heart disease reported good or better quality of life, with notable findings on physical activity and mental health.
Older adults with higher BMI and better diet quality experienced a slower decline in depressive symptoms over a 4-year period, suggesting a potential protective effect.