1. Anal cancer incidence is increasing among older white and Hispanic women, especially those over 65 years old.
2. The study utilized the SEER database to analyze temporal trends.
3. Current screening guidelines do not encompass the older female demographic experiencing rising incidence rates.
4. HPV is implicated in approximately 90% of anal cancer cases.
5. Anal cancer constitutes approximately 1% of all gastrointestinal malignancies.

Source: DDW 2025