Study reveals hospital variation in SGLT2i prescriptions, with only 11 of 518 hospitals (2.1%) achieving ≥50% prescription rates while 232 hospitals (44.8%) prescribed to fewer than 10% of eligible heart failure patients, highlighting an implementation gap in evidence-based therapy.
Post-stroke patients taking GLP-1 or SGLT2 medications showed a 74% lower mortality risk and 84% lower heart attack risk over 3 years compared to untreated peers.
Conexiant
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Liver tissue experiments in space could lead to viable alternatives for transplantation, leveraging unique conditions in low Earth orbit. Source: [insert source here]
AstraZeneca's early-stage trial of an experimental weight-loss pill from Eccogene showed promise in safety and tolerability, paving the way for Phase II trials to reduce body weight in obese and overweight individuals.
Despite achieving a 33.8% implementation rate of its recommendations versus 24.3% in usual care, a novel kidney action team intervention failed to improve outcomes in 4,003 hospitalized patients with acute kidney injury - highlighting the complex challenge of translating increased diagnostic testing into better clinical results.
The combination of adagrasib and cetuximab may show clinical activity and promising survival outcomes in patients with metastatic, heavily pretreated, KRAS G12C–mutated colorectal cancer.