July 07, 2025

Saliva Test May Signal Diabetes-Linked Metabolic Changes

Salivary enzyme levels tied to AMY1 gene copy number may help indicate type 2 diabetes or prediabetes status, new cross-sectional study suggests.

Conexiant

July 07, 2025

Cagrilintide–Semaglutide Yields Weight, A1c Gains

Once-weekly cagrilintide–semaglutide significantly reduced weight and improved glycemic control in adults with type 2 diabetes in the REDEFINE 2 trial.

Conexiant

July 07, 2025

Gene-Starch Interaction Alters Oral Bacteria Balance

A new study found that genetic differences in the AMY1 gene, which affects salivary amylase production, along with dietary starch, influence the types and diversity of bacteria that form in oral biofilms—key players in dental caries and gum disease.

Conexiant

July 03, 2025

Celiac, Thyroid Diseases Linked to Diabetes Risk

A large US-based study found that people with celiac disease, hyperthyroidism, or hypothyroidism face a two- to threefold increased risk of developing type 1 diabetes, with the highest risk seen in children.

Conexiant

June 30, 2025

Online Genetic Testing Platform Demonstrates Notable Engagement Among Patients With Young-Onset Colorectal Cancer

In a pilot study being presented at the 2025 ASCO Annual Meeting, Moskowitz et al developed and evaluated an online platform that enables patients with young-onset colorectal cancer to access educatio...

The ASCO Post

June 30, 2025

Reduced-Dose Chemoradiotherapy in Early-Stage Anal Cancer

In a UK phase II trial (PLATO-ACT4) reported in The Lancet Oncology, Gilbert et al compared short-term response rates of standard- vs reduced-dose chemoradiotherapy in patients with localized squamous...

The ASCO Post

June 30, 2025

Reduced-Dose Chemoradiotherapy for Early-Stage Anal Cancer

In a UK phase II trial (PLATO-ACT4) reported in The Lancet Oncology, Gilbert et al evaluated whether short-term results showed good complete response rates with both standard-dose and reduced-dose che...

The ASCO Post

June 30, 2025

Patterns of ICI Use and Survival Outcomes in Metastatic Colorectal Cancer

In a U.S. population–based cohort study reported in JAMA Network Open, Bari et al identified patterns of immune checkpoint inhibitor (ICI) use and survival outcomes among patients with metastatic colo...

The ASCO Post

June 30, 2025

Childhood Exposure to Bacterial Toxin May Trigger Early-Onset Colorectal Cancer

Researchers may have identified a bacterial toxin as a potential factor contributing to the concerning rise in early-onset colorectal cancer.

The ASCO Post