- Higher risk in T1DM: Patients with T1DM have persistently higher rates of DRD and vision-threatening disease than those with T2DM (≈3–6× higher odds depending on subtype).
- Rising prevalence despite care advances: DRD prevalence is increasing in both T1DM and T2DM populations, likely reflecting longer survival and growing diabetes prevalence.
- Encouraging decline in incidence: Incidence of DRD and VTDR is decreasing overall, especially in T1DM, suggesting benefits from improved diabetes management and screening.
- Persistent burden of vision-threatening disease: VTDR, DME, and PDR remain significantly more common in T1DM, underscoring need for aggressive screening and control.
- Narrowing gap between T1DM and T2DM: The disparity in DRD incidence is decreasing over time, but not eliminated, indicating ongoing need for targeted prevention strategies.
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