1. Kidney Disease: Improving Global Outcomes (KDIGO)-based bundle reduced moderate–severe acute kidney injury (14.4% vs 22.3%).
2. Biomarkers enabled targeted high-risk patient selection.
3. Hemodynamic optimization and nephrotoxin avoidance were central.
4. No increase in adverse events.
5. Supports routine postoperative acute kidney injury prevention protocols.

Source: The Lancet Study, Commentary