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Conexiant chevron_right Rheumatology chevron_right Lung Disease Complicates RA Care
From the Journals

Lung Disease Complicates RA Care

Patients with chronic lung disease had numerically lower remission rates and substantially more serious adverse events in a 5-year Japanese registry study of late-onset rheumatoid arthritis.

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  • Five-year SDAI remission rates were 30% in patients with chronic lung disease vs 44% in those without chronic lung disease.
  • Patients with chronic lung disease had a 2.5-fold higher risk of serious adverse events during follow-up.
  • Nonadherence to treat-to-target because of comorbidities or adverse events occurred in 34% of patients with chronic lung disease vs 19% without chronic lung disease.
  • Interstitial lung disease worsened in 10 of 31 patients with baseline ILD, and three patients died following ILD exacerbation outside the formal observation period.
  • The prospective study included 197 methotrexate-naïve patients with late-onset rheumatoid arthritis from a single Japanese center followed for 5 years.

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