New 2024 EULAR recommendations offer evidence-based guidance for the use of antirheumatic drugs during pregnancy, lactation, and conception planning in patients with rheumatic and musculoskeletal diseases.
A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.
A Swedish study found that patients with knee or hip osteoarthritis who became unwilling to have joint replacement after a 3-month education and exercise program were significantly less likely to undergo surgery over the next several years.
Older adults who stopped antipsychotic medications after hospitalization had fewer rehospitalizations, less delirium, and lower mortality, according to a large U.S. study using real-world Medicare data.
Children with lupus nephritis had altered IgG sugar chains that impaired kidney cell metabolism, and removing those sugars reversed the injury in lab tests.
In a UK-wide analysis of nearly 2 million patients, researchers found that “a fifth of patients receiving corticosteroids accounted for over 80% of oral and inhaled corticosteroid prescribing,” highlighting concentrated use and variable treatment persistence across formulations.