When fiber metabolism falters in lupus, the microbiome may start dining on the host instead. This week: mucin-munching bugs, brain-delivered DHA with no cognitive payoff, and lipid-loaded MS lesions that may not be innocent bystanders.
Published evidence linked liraglutide and semaglutide to improvements in psoriasis severity, inflammatory markers, and metabolic outcomes, while evidence in psoriatic arthritis remained sparse.
In a nationwide Finnish cohort, patients with atrial fibrillation and gout had higher ischemic stroke rates, while urate-lowering therapy was associated with lower stroke rates.
Preoperative use was associated with fewer revisions and no increase in short-term complications among patients with obesity, although benefits appeared concentrated in select subgroups.
Acidic gum beat sugar-free at cranking out nitric oxide from beetroot juice — exactly backward from what test-tube studies predicted. Also this week: a sleep gene that ignores amyloid, and jackfruit sap moonlighting as a bone-building drug delivery system.
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In a small open-label randomized trial, 2 platelet-rich plasma injections were associated with greater 6-month improvements in pain and function than corticosteroid injection or oral aceclofenac among patients awaiting knee arthroplasty.
A Geneva registry study points surgeons toward residual pain over functional limitation as the outcome that tracks patient satisfaction one year after hip or knee replacement.
Analysis of East Asian genetic data found a modest inverse association between rheumatoid arthritis susceptibility and periodontitis risk, though researchers said the findings require confirmation in independent cohorts.
Nearly 40% of registry patients would have been excluded from phase 3 randomized controlled trials, with exclusion criteria distributed unevenly across drug classes.