In a paradigm shift for treating acute CPPD crystal arthritis, the 2023 COLCHICORT trial showed prednisone matched colchicine's efficacy with better tolerability in older patients, challenging long-held treatment assumptions.
In a paradigm shift for treating acute CPPD crystal arthritis, the 2023 COLCHICORT trial showed prednisone matched colchicine's efficacy with better tolerability in older patients, challenging long-held treatment assumptions.
While total knee arthroplasty traditionally aims for neutral mechanical alignment, researchers found that maintaining a patient's natural preoperative alignment was associated with significantly better patient-reported outcomes, with scores improving by approximately 10% when natural alignment was preserved.
A recent trial reveals how a virtual yoga intervention led to reduced pain medication use and improved back function in adults with chronic low back pain.
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In this 68-week trial, semaglutide not only achieved 13.7% weight reduction but also decreased NSAID use and improved walking distance by 42.6 meters compared to placebo in patients with knee osteoarthritis, suggesting potential benefits beyond weight loss.
While biological therapies for RA show similar efficacy rates (~60% ACR20, ~40% ACR50, ~20% ACR70), researchers highlight safety profiles as a critical factor in guiding rheumatoid arthritis treatment selection.