June 30, 2025

Can Typos Change a Diagnosis?

Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.

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June 25, 2025

Top Physical Therapies for Knee OA

A large-scale analysis of physical therapies for knee osteoarthritis found knee bracing, hydrotherapy, and exercise to be the most effective options for reducing pain and improving function.

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June 23, 2025

Sitting-Rising Test Predicts Long-Term Mortality Risk

A 12-year study of over 4,000 adults found that poor performance on a basic sitting and rising test was strongly linked to increased risk of death from natural and cardiovascular causes.

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June 23, 2025

Chronic Pain Persists After Joint Replacement Surgery

Roughly 1 in 5 knee replacement patients still experience joint pain after three months, according to a large analysis of nearly 600,000 surgeries.

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June 19, 2025

GLP-1 Use Associated with Less Pain, Fatigue

At the EULAR 2025 Congress, researchers reported that GLP-1 receptor agonists were linked to reduced opioid use, pain, and fatigue in fibromyalgia patients based on a large real-world analysis.

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June 12, 2025

Gene Variants Linked to CPPD Risk

A large genetic study in U.S. veterans has identified ENPP1 and RNF144B as genes associated with calcium pyrophosphate deposition disease, suggesting potential for targeted treatment approaches.

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June 12, 2025

Circulating miR-126-3p Linked to Knee OA

Plasma levels of miR-126-3p are elevated in radiographic knee osteoarthritis and may attenuate disease severity by reducing angiogenesis.

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June 12, 2025

DMARD Therapy Linked to Less Pain Sensitivity

Improvements in pressure pain thresholds were associated with reductions in disease activity.

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June 10, 2025

New Guidelines Challenge BMI Thresholds for Knee Surgery

ACR/AAHKS guideline conditionally recommends against delaying total knee arthroplasty based solely on BMI, prompting debate among orthopedic specialists.

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