1. Study analyzed blood genomes from 23 chemotherapy-treated patients.
2. Elevated somatic mutations noted in 17 patients.
3. Mutation signatures linked to specific chemotherapy agents.
4. 5-fluorouracil mutations occurred only in lymphoid cells.
5. Study highlights long-term genomic impact of chemotherapy.
6. Oxaliplatin caused fewer mutations compared to other agents.
7. Some drugs affect specific blood cell types differently.
8. Research suggests chemotherapy may accelerate hematopoietic aging.

Source: Nature Genetics