December 20, 2024

Will CAR T-Cell Therapy Be the Magic Bullet for My Multiple Myeloma?

“Intense pain on the right side of my lower rib cage, in 2020, sent me first to my chiropractor for relief and then to my primary care provider for tests. Because of the location of the pain, the chir...

The ASCO Post

December 20, 2024

Riluzole Shows Promise in Reversing Cognitive Decline from Radiation Therapy

Boosting brain-derived neurotrophic factor (BDNF) with riluzole may mitigate cognitive dysfunction from radiation therapy.

Conexiant

December 20, 2024

Small HCQ Study Falls to Retraction

When combining hydroxychloroquine with azithromycin, researchers reported 100% virological cure by day 6 compared to 57.1% with hydroxychloroquine alone and 12.5% in controls - though the now-retracted study's small sample included just 6 patients receiving both drugs.

Conexiant

December 20, 2024

In Treatment of Transplant-Ineligible Myeloma, Addition of Isatuximab Improves Outcomes

In the phase III IMROZ trial, the addition of the anti-CD38 monoclonal antibody isatuximab-irfc to bortezomib, lenalidomide, and dexamethasone (VRd) was more effective than VRd alone as initial therap...

The ASCO Post

December 20, 2024

Use of Ibrutinib in Early-Stage Chronic Lymphocytic Leukemia

In a German phase III trial (CLL12), reported in the Journal of Clinical Oncology, Langerbeins et al found that ibrutinib prolonged the time to symptomatic disease in patients with early-stage chronic...

The ASCO Post

December 20, 2024

POI Guidelines See First Major Update Since 2015

Four medical societies have revised their diagnostic criteria for premature ovarian insufficiency, now requiring only one elevated FSH test instead of two, while reporting a higher than previously known prevalence rate of 3.5% among women.

Conexiant

December 19, 2024

Detection of Occult Maternal Cancer Through Prenatal Cell-Free DNA Sequencing

In the IDENTIFY study, reported in The New England Journal of Medicine, Turriff et al found a high incidence of maternal occult cancer associated with unusual or nonreportable prenatal cell-free DNA f...

The ASCO Post

December 19, 2024

Plant-Based Meat Study Reveals Depression Link

A study on UK vegetarians and plant-based meat alternatives revealed surprising health outcomes related to depression, irritable bowel syndrome, and blood biochemistry levels.

Conexiant

December 19, 2024

FDA Approves Ensartinib for ALK- Positive Locally Advanced or Metastatic NSCLC

The U.S. Food and Drug Administration (FDA) recently approved the anaplastic lymphoma kinase (ALK) inhibitor ensartinib (Ensacove) for adults with ALK-positive locally advanced or metastatic non–small...

The ASCO Post