Superagers aged 80 years and older demonstrate a unique neurobiological profile associated with successful aging: preserved memory and distinct brain anatomy, including thicker cortical regions and lower tau pathology.
Circulating Insulin-like peptide 5 concentrations may reflect colonic exposure to bile acids and help stratify treatment response in patients with chronic diarrhoea, including those with irritable bowel syndrome with diarrhoea and bile acid diarrhoea.
Each additional 1,000 daily steps a day may be associated with a reduction in major adverse cardiovascular events among patients with hypertension, with benefits evident at step counts well below 10,000 steps per day.
Hidradenitis suppurativa is associated with increased risks of depression and anxiety across all treatment levels, highlighting the importance of proactive psychiatric screening in dermatologic care.
Nearly 1 in 10 individuals with myalgic encephalomyelitis/chronic fatigue syndrome reported voice or speech changes in a recent survey, despite not being directly asked about these symptoms.
Patients with psoriatic arthritis consistently identify nonjoint symptoms such as dactylitis, psoriasis, and uveitis, demonstrating the clinical utility of patient-reported outcome measures.
Analysis of electronic health records reveals that delays in clinical hypertension diagnosis persist despite frequent outpatient visits and are linked to increased cardiovascular event rates.