Researchers found greater reductions in body mass index and participant-reported hunger scores with setmelanotide than with placebo, although adverse and serious adverse events were more frequent in the setmelanotide group; only one serious adverse event was considered treatment-related.
Application of newly proposed GRAPPA and EULAR criteria in a longitudinal cohort identified progressively smaller groups of patients with early psoriatic arthritis who experienced persistently worse patient-reported outcomes.
Frequent CLDN18.2 expression was associated with gastric-type differentiation and reduced spread through air spaces in pulmonary invasive mucinous adenocarcinoma.
Conexiant
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The association with coronary artery calcium persisted following extensive adjustment, whereas carotid plaque findings may be largely explained by cardiometabolic risk factors.
A real-world cohort found faster early skin responses with ixekizumab than with guselkumab or ustekinumab following secukinumab treatment failure, while all three biologics demonstrated favorable safety.
International cohort study found physical function declined most rapidly before mortality, while socioeconomic status was associated with more favorable multidomain trajectories.