Newborns have higher levels of phosphorylated tau217 in their blood than even patients with Alzheimer’s disease, a new study finds, raising new questions about the dual role of tau in brain development and degeneration.
A large cohort study comparing methadone and buprenorphine for opioid use disorder found no significant difference in reducing illicit opioid use, but methadone showed better treatment retention after one year.
Once-weekly cagrilintide–semaglutide significantly reduced weight and improved glycemic control in adults with type 2 diabetes in the REDEFINE 2 trial.
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Vitamin C may help thicken human skin by epigenetically activating genes involved in cell growth, according to new research using a lab-grown human skin model. The study found that vitamin C, or L-ascorbic acid, promotes epidermal proliferation by modifying gene activity through DNA demethylation.
A systematic review and network meta-analysis of clinical trials found that several biologic and small-molecule therapies provided short-term improvement in adults with moderate to severe hidradenitis suppurativa, a chronic inflammatory skin disease.