New research in mice suggests that parental alcohol use before conception may predispose male offspring to increased liver cancer susceptibility through epigenetic changes in mitochondrial function. The study identifies mitochondrial dysfunction and inflammation as key mechanisms, with dual-parental exposure producing the most severe effects.
The drug development tool offers an alternative, clinically meaningful endpoint in clinical trials that evaluate pharmacologic treatments for alcohol use disorder.
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Researchers examined systemic absorption, metabolism, and excretion of tattoo ink tracers, providing evidence for a cutaneous first-pass effect and measuring systemic exposure levels.
Researchers examined the effects of broccoli sprout extract on fasting glucose in prediabetes and observed variability in glycemic response potentially linked to microbiota composition.
FDA approves Merilog (insulin-aspart-szjj) as the first rapid-acting insulin biosimilar to Novolog for glycemic control in adult and pediatric diabetes patients, expanding treatment accessibility.