Fetal hematopoietic stem cells in Down syndrome are 'primed' for differentiation, as revealed by single-cell multi-omics of over 1.1 million cells, potentially explaining early hematological abnormalities.
French study reveals epidermal necrolysis has 34% one-year mortality rate, with postdischarge deaths linked to acute complications rather than initial disease severity.
Systemic chemotherapy is the most common method of treatment for cancer. Newer antineoplastic agents offer improved survival rates for aggressive malignancies; however, in some cases they may cause ocular side effects. This article aims to review the various ocular effects of several classes of systemic chemotherapy drugs, including immune checkpoint inhibitors (ICIs), ALK inhibitors, MEK inhibitors, BRAF inhibitors, and EGFR inhibitors.
Real-world data analysis reveals early selexipag addition may reduce hospitalization risk in PAH patients, but study design limitations warrant cautious interpretation.
Misdiagnosis can lead to inappropriate treatment, potentially subjecting patients to unnecessary toxicity or, conversely, inadequate treatment for a life-threatening cancer.
Conexiant
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A recent study in Pennsylvania wastewater revealed genetic links between Salmonella isolates and a concurrent outbreak, showcasing the potential of sewage monitoring to aid in public health surveillance.