A new study has found that endoscopic retrograde cholangiopancreatography (ERCP) with minor papilla endoscopic sphincterotomy (miES) does not provide any benefit in preventing acute pancreatitis in patients with pancreas divisum. Despite prior retrospective studies suggesting its effectiveness, the randomized trial showed no significant difference in acute pancreatitis recurrence, pancreas-related pain, chronic pancreatitis, diabetes, or exocrine pancreatic insufficiency between the miES and sham procedure group. These findings challenge the long-standing advocacy for this intervention and are likely to impact current treatment guidelines.

Source: DDW