5 Key Takeaways

• 1

  A new guideline from pediatric gastroenterology societies addresses irritable bowel syndrome and functional abdominal pain in children and adolescents.

• 2

  The guideline includes 25 recommendations based on 86 randomized controlled trials, emphasizing mind–body interventions.

• 3

  Gut-directed hypnotherapy and cognitive behavioral therapy are strongly supported for reducing pain intensity in pediatric patients.

• 4

  Conditional recommendations include multistrain probiotics, enteric-coated peppermint oil, and low-dose amitriptyline for select patients.

• 5

  The authors call for more pediatric-specific research to address evidence gaps in treatments commonly used for adults.