1. The Mediterranean diet reduced IBS symptom severity within two weeks, demonstrating both noninferiority and superiority to traditional dietary advice.
2. Sixty-two percent of participants on the Mediterranean diet achieved a 50-point or more IBS-SSS reduction versus 42% in the control group.
3. Participants adhering to the Mediterranean diet consumed higher levels of fiber, folate, magnesium, and oligosaccharides.
4. Both groups showed improvements in mood and quality of life, supporting a role for dietary intervention in the gut–brain axis.
5. The Mediterranean diet offers an evidence-based, first-line dietary option for managing IBS symptoms in clinical practice.

Source: Annals of Internal Medicine