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Conexiant chevron_right Gastroenterology chevron_right Intestinal Ultrasound Adds Independent Prognostic Signal Beyond Clinical Scores in IBD Pregnancy
From the Journals

Intestinal Ultrasound Offers Prognostic Value in IBD Pregnancy

"We rely very little on symptoms in pregnancy—they’re so unreliable—and instead target fecal calprotectin under 100 and sonographic remission."

Conexiant
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  1. Active disease on IUS during pregnancy was associated with 4-fold increased risk of prematurity and 2-fold increased risk of low birth weight, even after adjusting for clinical activity and fecal calprotectin. A bowel wall thickness over 6mm in the second trimester was the strongest predictor of adverse outcomes.

  2. Agreement between clinical scores and objective markers was minimal to weak throughout pregnancy. 

  3. IUS and FCP are complementary. Using both tools together provides the most accurate disease activity assessment during pregnancy.

  4. Women in objective remission in the first trimester had an 85.5% chance of maintaining remission in the second trimester. Those with active disease on IUS or elevated FCP in early pregnancy had 4-fold increased risk of disease activity later in pregnancy.

  5. Active disease on IUS was associated with adverse outcomes including gestational diabetes and preeclampsia, independent of clinical and biochemical markers. 

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