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Conexiant chevron_right Gastroenterology chevron_right Gluten-Free Diet Restores Key Epigenetic Marker in Coeliac Disease
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Gluten-Free Diet Restores Key Epigenetic Marker in Coeliac Disease

LINE-1 hypomethylation, a reversible feature of Coeliac disease inflammation, offers new insights into cancer prevention.

Conexiant
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Hypomethylation of LINE-1 elements is a significant epigenetic marker related to the inflammatory response in coeliac disease and its associated small bowel adenocarcinoma. The study reveals potential reversibility of these epigenetic changes through dietary intervention, providing insights into molecular mechanisms underlying autoimmune disorders and cancer development.

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