5 Key Takeaways

• 1

  The AGA released updated guidelines for diagnosing and managing cyclic vomiting syndrome (CVS) in adults, aiming to improve recognition and treatment.

• 2

  CVS affects an estimated 2% of adults in the U.S. and is characterized by recurrent episodes of intense nausea and vomiting.

• 3

  The guidelines emphasize using Rome IV criteria for diagnosis and distinguishing between mild and moderate-severe CVS.

• 4

  Management recommendations include lifestyle modifications, prophylactic therapy with tricyclic antidepressants, and abortive treatments during the prodromal phase.

• 5

  The guidelines also address cannabis use in CVS patients and highlight the need for further research on CVS pathophysiology and clinical outcomes.