Alcohol consumption has widespread harmful effects on the digestive system, contributing to a significant global mortality rate. Chronic ethanol intake leads to pathological changes in the gastrointestinal tract, liver, pancreas, and gallbladder, increasing the risk of conditions such as liver cirrhosis, pancreatitis, and esophageal cancer. Women are more susceptible to alcohol-related damage due to lower body water content and reduced first-pass metabolism. A review published in the Journal of Translational Gastroenterology underscored the importance of minimizing alcohol intake for digestive health and seeking prompt medical evaluation for suspected overconsumption.