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Conexiant chevron_right Gastroenterology chevron_right AGA Updates HBV Reactivation Prophylaxis Guidelines
Clinical Guidelines From the Journals

AGA Updates HBV Reactivation Prophylaxis Guidelines

New evidence-based recommendations stratify antiviral prophylaxis across immunotherapies, with clear risk-based protocols for patient management.

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  1. The AGA released updated clinical practice guidelines for hepatitis B virus reactivation prevention and treatment. 
  2. Antiviral prophylaxis is strongly recommended for high-risk patients.
  3. A conditional recommendation for moderate-risk (1% to 10%) and low-risk patients (under 1%) was made.
  4. Universal testing for HBsAg, anti-HBc, and anti-HBs is strongly recommended for all adults aged 18 plus. 
  5. HBV reactivation risk categorization is based on serological status and exposure.
  6. Antiviral prophylaxis reduces HBV reactivation risk and hepatitis flare rates, but potential adverse effects exist. 

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