5 Key Takeaways

• 1

  The American Gastroenterological Association updated guidelines for preventing hepatitis B virus reactivation in at-risk patients.

• 2

  Strong recommendations for antiviral prophylaxis are made for high-risk patients, with conditional recommendations for moderate and low-risk patients.

• 3

  Universal testing for HBsAg, anti-HBc, and anti-HBs is strongly recommended for all adults aged 18 and older.

• 4

  Antiviral prophylaxis reduces HBV reactivation risk by 82% and hepatitis flare rates by 72%, but may have adverse effects.

• 5

  The guideline panel plans to update recommendations in 5 years to include new therapies and data.