Researchers at the National Cancer Institute developed poly-metabolite scores that can distinguish between high and low ultraprocessed food (UPF) diets. These scores were validated in both observational and experimental settings, providing objective measures of UPF consumption, which is significant due to the prevalence of UPF in the American diet. The study highlights specific metabolic signatures, including four key metabolites, that are associated with UPF intake and may advance epidemiological research on UPF and health.

Source: PLOS Medicine