From 2019 to 2021, U.S. emergency departments saw a 125.4% rise in synthetic opioid overdoses, highlighting shifting trends in hospital use related to opioids during and before the COVID-19 pandemic.
Researchers found that USPSTF guidelines inadequately stratify preeclampsia risk among pregnant patients, particularly those at moderate risk, and therefore limit the utility of aspirin prophylaxis recommendations.
A twin study found that individuals who consumed most of their daily calories later in their personal circadian rhythm had lower insulin sensitivity and greater insulin resistance, with genetics playing a role in meal timing behavior.
Researchers used blood proteins to estimate the biological age of 11 organs in over 44,000 people, revealing that older brain and immune systems were linked to higher disease and death risks, while younger ones predicted longer life.
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A 78-week international trial found that a once-weekly insulin injection effectively lowered blood sugar in adults with type 2 diabetes, performing similarly to a once-daily insulin regimen with comparable safety.
Researchers found vaporized nicotine products more effective than nicotine replacement therapy for smoking cessation among socioeconomically disadvantaged adults.
Researchers found that semaglutide and tirzepatide were associated with reduced risks of dementia, stroke, and all-cause mortality in patients with type 2 diabetes and obesity.
Researchers found that unopposed estrogen therapy was linked to reduced young-onset breast cancer risk, while estrogen plus progestin therapy increased risk in certain subgroups.