A new phase 3 study found that daily oral upadacitinib 15 mg, combined with a shorter 26-week steroid taper, improved sustained remission rates and reduced steroid use in patients with giant-cell arteritis.
A study of older adults found that specific oral bacteria were linked to cognitive performance and genetic risk for Alzheimer’s, while other microbes showed stronger associations in people with mild cognitive impairment.
A randomized trial found that using a natural cycle to prepare the endometrium for frozen embryo transfer in ovulatory women led to higher live birth rates and fewer complications compared to hormone replacement therapy.
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FDA approves Ekterly (sebetralstat), the first oral on-demand treatment for hereditary angioedema, shown in trials to provide faster symptom relief and eliminate the need for injection.
Newborns have higher levels of phosphorylated tau217 in their blood than even patients with Alzheimer’s disease, a new study finds, raising new questions about the dual role of tau in brain development and degeneration.
A systematic review and network meta-analysis of clinical trials found that several biologic and small-molecule therapies provided short-term improvement in adults with moderate to severe hidradenitis suppurativa, a chronic inflammatory skin disease.