This study found that the human hippocampus continues to perform surprisingly sophisticated sensory and language processing even under general anesthesia-induced unconsciousness. Using Neuropixels recordings from patients undergoing epilepsy surgery, researchers showed that hippocampal neurons could distinguish auditory “oddball” tones, adapt their responses over time, and encode semantic and grammatical features of spoken language—including contextual information about upcoming words. These findings suggest that complex neural computations and forms of learning can persist without conscious awareness, challenging theories that higher-order cognition strictly depends on consciousness.
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