A 52-week randomized clinical trial found no significant difference between methotrexate and placebo in reducing pain or effusion-synovitis in patients with inflammatory knee osteoarthritis.
The UK hospital study of over 80,000 patients found that certain opioids, including morphine and oxycodone, carried a higher risk of severe constipation compared with others.
Large language models used in clinical decision-making may offer different treatment recommendations depending on how a patient writes their message—even when the medical facts remain unchanged.
A large-scale analysis of physical therapies for knee osteoarthritis found knee bracing, hydrotherapy, and exercise to be the most effective options for reducing pain and improving function.
A 12-year study of over 4,000 adults found that poor performance on a basic sitting and rising test was strongly linked to increased risk of death from natural and cardiovascular causes.
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A recent study published in The New England Journal of Medicine compared total hip replacement with resistance training in patients with severe hip osteoarthritis, showing significant improvements in pain and function in the hip replacement group.
A 20-year study reveals that patients with osteoarthritis have a higher risk of severe multimorbidity, emphasizing the need for comprehensive health care strategies beyond joint health.
Omega-3 supplementation has shown potential in reducing inflammation and improving symptoms in osteoarthritis, though further research is needed to confirm its efficacy.