- Do not focus on disease alone: Reproductive outcomes are shaped by disease activity, medication use, access to care, and social determinants—not just immunologic factors.
- Assess reproductive goals routinely: Ask about pregnancy preferences early and regularly, especially when prescribing teratogenic medications.
- Optimize disease control before pregnancy: Well-controlled disease for 3–6 months prior to conception is a key predictor of better outcomes.
- Know medication safety basics: Some therapies are compatible with pregnancy, while others (e.g., methotrexate, mycophenolate) are contraindicated; evidence gaps remain substantial.
- Coordinate care across disciplines: Strong collaboration with ObGyn, primary care, and specialists is essential to address contraception, pregnancy planning, and perinatal management.
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