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Conexiant chevron_right Rheumatology chevron_right mRNA Boosters Drive Antibody Evolution in Immunosuppressed Patients
From the Journals

mRNA Boosters Drive Antibody Evolution in Immunosuppressed Patients

Successive mRNA vaccinations enhanced cross-variant antibody evolution in immunosuppressed patients, though responses varied by treatment type, according to a new study.

Conexiant
article Full Article subject Summary summarize Notecard
  1. SARS-CoV-2 antibody repertoire evolution after mRNA vaccinations in immunosuppressed patients.  
  2. Impact of immunosuppressive treatments on cross-variant antibody evolution.
  3. Minimal to no antibody evolution in patients receiving anti-CD20 therapy.
  4. Prior SARS-CoV-2 infections accelerated emergence of BA.1 RBD reactivity.
  5. Implications for vaccination strategies among patients with immune-mediated inflammatory diseases.

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