- 62.5% of children with SLE successfully tapered glucocorticoids in the first year.
- Disease activity assessed using SLEDAI.
- 23 patients (28.8%) experienced disease flares during the study.
- Initial average glucocorticoid dose was 0.94 mg/kg/day.
- Presence of anti-dsDNA antibodies increased flare risk post-treatment.
Source: Lupus Science & Medicine