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Conexiant chevron_right Rheumatology chevron_right Immunosuppressive Therapy Withdrawal and Renal Relapse Risks
From the Journals

Immunosuppressive Therapy Withdrawal and Renal Relapse Risks

Study finds prolonged immunosuppressive therapy duration and gradual tapering reduce renal relapse risk in proliferative lupus nephritis.

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A recent study assessed the risk of renal relapse in patients with lupus nephritis who discontinued immunosuppressive therapy after maintaining complete renal response for at least 48 months. The study found that patients aged 34 years or younger had a significantly increased risk of relapse, while those with a longer duration of immunosuppressive therapy before discontinuation and those who achieved complete remission and underwent gradual tapering had a reduced risk of relapse. The findings provide insights for optimizing immunosuppressive therapy withdrawal strategies in lupus nephritis management.

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