1. A study on U.S. veterans identified genes ENPP1 and RNF144B linked to chondrocalcinosis.
2. The genetic variations provide insights into potential therapeutic targets for CPPD.
3. The study focused on calcium pyrophosphate deposition disease, a form of crystal arthritis.
4. ENPP1 may represent a potential therapeutic target for CPPD.
5. Limitations of the study include potential underascertainment of disease in controls and a lack of female representation.

Source: Annals of the Rheumatic Diseases