- Anti-CD146 autoantibodies were identified as a new biomarker in systemic sclerosis.
- Anti-CD146 autoantibodies were more common in systemic sclerosis patients than healthy controls.
- Positivity was significantly linked to occupational silica exposure.
- 57% of dust-exposed workers had detectable anti-CD146 autoantibodies in a validation cohort.
- Anti-CD146 autoantibodies may help identify occupationally associated systemic sclerosis earlier.
Source: ACR Open Rheumatology
