In a randomized clinical trial of 995 university students with psychological distress, a 12-week conversational artificial intelligence platform was associated with greater reductions in anxiety and improvements in well-being compared with both face-to-face group therapy and a waiting list control, and greater reductions in depression and life satisfaction vs control, with no effect on posttraumatic stress disorder symptoms. Therapeutic alliance with the artificial intelligence agent was significantly associated with engagement and symptom improvement, supporting a mechanistic role for

Source: JAMA Network Open