A randomized trial of 160 adults with depression and obesity found no improvement in mood symptoms from adding simvastatin to escitalopram, though the statin significantly lowered cholesterol and inflammation levels.
A newly published study showed that a metabolite of paracetamol can directly block sodium channels in peripheral pain-sensing neurons, helping reduce pain without acting on the brain.
A Phase I study of intrathecal resiniferatoxin in patients with advanced cancer pain shows promising reductions in pain and opioid use, with durable effects and manageable side effects.
A new study found that a shorter time gap between melatonin production and sleep midpoints may be linked to longer survival among women with advanced breast cancer.
A large U.S. hospital database study found that postoperative urinary retention after knee replacement is rising and linked to complications, especially in older men and patients with certain health conditions.
New research found that first-time mothers experienced substantial sleep disruption for more than 3 months after childbirth, even as total sleep time gradually recovered.
A cohort study of more than 2 million individuals found that autism spectrum disorder was associated with a more than fourfold increased risk of Parkinson disease before age 50 years, even after adjusting for psychiatric medication use and depression.