In a retrospective analysis of prospectively collected data from 1,297 survivors of oropharyngeal cancer, researchers found that selected patient-reported symptoms from the MD Anderson Symptom Inventory–Head and Neck module were associated with later development of hypoglossal nerve neuropathy. Higher MDASI-HN-NERVE composite scores and persistent speech or voice symptoms during early recovery were linked to increased long-term neuropathy risk, suggesting that longitudinal symptom surveillance may help support early risk stratification in survivorship care.