- Engineered E. coli bacteria can perform Lossen rearrangement.
- Plastic waste (PET) is converted to paracetamol.
- Para-aminobenzoic acid (PABA) is synthesized within the bacteria.
- High yields of paracetamol (92%) achieved under optimized conditions.
- The process integrates synthetic reactions with microbial metabolism.
- Future focus on scaling for industrial use.
Source: Nature Chemistry