5 Key Takeaways

• 1

  The RESOLVE trial showed underrepresentation of Hispanic participants, highlighting inequities in decentralized trials.

• 2

  Decentralized trials may shift participation barriers rather than eliminate them, affecting trial inclusivity.

• 3

  Remote trials rely on technology that may disadvantage populations with lower digital fluency or access.

• 4

  Hybrid trial models can enhance diversity by combining in-person and remote participation options.

• 5

  Trial design must prioritize representativeness to ensure findings are generalizable across diverse populations.