Can Finerenone Alter Glomerular Disease Trajectory?
Conexiant
June 5, 2026
The FIND-CKD trial included 903 participants with glomerular diseases, assessing the effects of finerenone versus placebo.
Finerenone reduced the eGFR decline by 1.22 mL/min/1.73 m² per year after 3 months compared to placebo.
In the immunoglobulin A nephropathy subgroup, finerenone decreased urinary albumin-to-creatinine ratio by 47%.
Serious adverse events were similar between finerenone (20%) and placebo (21%) groups, with low rates of hyperkalemia.
The study faced limitations, including reliance on investigator-reported diagnoses and lack of biopsy confirmation for many participants.
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.
Stay up to date with the latest clinical headlines and other information tailored to your specialty.
Thank you for signing up for the Daily News alerts. You will begin receiving them shortly.
Editor
Affiliations:
Specialties:
Areas of Expertise: