Researchers have developed a noninvasive blood test that analyzes methylation patterns in cell-free DNA to detect signs of liver allograft injury with unprecedented precision in liver transplant patients. The test offers an early warning system, identifying specific liver cell damage and providing a clearer view of the transplant's condition before symptoms emerge. The method could complement or reduce the need for invasive liver biopsies, potentially serving as a promising tool for personalized, cell-specific monitoring after liver transplantation.
Source: Nature Communications