1. Initiate anal cancer screening at age 35 for men who have sex with men with HIV.
2. Multiple screening methods and intervals were evaluated to guide recommendations.
3. Without screening, the model projected 4,064 anal cancer cases and 680 deaths over the lifetime of 100,000 men.
4. Anal cancer incidence in MSM with HIV was approximately 45 times higher compared to men without HIV.
5. Value-based prioritization may optimize screening use and resource allocation.

Source: Annals of Internal Medicine