- Adequate cleansing was similar across regimens: 1-L, 2-L, and 4-L PEG achieved comparable rates (~78%–82%), meeting the primary endpoint.
- High-quality cleansing favored the 1-L regimen: 47% vs 35% (2-L) and 37% (4-L), with a similar advantage in the right colon.
- Patient acceptability was highest with 1 L: Willingness to repeat was 84% vs 82% (2-L) and 68% (4-L).
- Adverse events were mostly mild but differed by regimen: Vomiting and thirst were more frequent with 1 L, while difficulty completing the preparation was more common with 4 L.
- Findings apply to stable hospitalized patients only: The trial excluded urgent colonoscopy and patients with severe or unstable conditions, limiting generalizability.
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