A large-scale randomized controlled trial compared Roux-en-Y gastric bypass, sleeve gastrectomy, and adjustable gastric banding in patients with severe obesity.
RYGB resulted in superior weight loss and quality-of-life outcomes at 3 years, making it the most cost-effective option. The study suggested RYGB should be the recommended bariatric surgery, with SG as an alternative, and AGB not as a standard treatment. The trial emphasized the need for long-term outcome assessments and comparative effectiveness data to guide evidence-based practice.
