In a cross-sectional analysis of 23,475 adults from the National Health and Nutrition Examination Survey (2009–2023), researchers identified an inverted U-shaped association between weekday sleep duration and estimated glucose disposal rate, a marker of insulin resistance, with optimal metabolic status observed at approximately 7.3 hours of sleep. Among participants with insufficient weekday sleep, moderate weekend catch-up sleep (1–2 hours) was associated with improved estimated glucose disposal rate, whereas excessive catch-up sleep (>2 hours) or longer baseline sleep duration was linked to poorer metabolic profiles, suggesting that consistent sleep patterns may be important for cardiometabolic health.

Source: BMJ Open Diabetes Research & Care