5 Key Takeaways

• 1

  The KEEPS Continuation Study found no long-term cognitive differences between hormone therapy and placebo groups.

• 2

  The study involved 275 women assessed approximately 10 years after the original KEEPS trial.

• 3

  Participants received either oral conjugated equine estrogens, transdermal estradiol, or placebo for 48 months.

• 4

  Cognitive performance was primarily predicted by baseline cognition and changes during the original trial.

• 5

  The study population included women who began hormone therapy within 3 years of their final menstrual period.