A systematic review analyzed 99 randomized clinical trials involving 6,582 adults, primarily overweight or with conditions like type 2 diabetes. It found that alternate-day fasting (ADF) led to significant but modest weight loss compared to other diets, averaging 3.4 kg. While ADF showed better lipid profiles, the study noted that long-term adherence was an issue, with only minor weight reductions after 24 weeks. The review emphasizes the need for further high-quality trials to assess long-term efficacy and cardiometabolic health outcomes.

Source: The BMJ